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GSEA was performed with the GSEAPY Python package (v.0.10.3)

How to Give a Vitamin B12 Shot Vitamin B12 is an essential nutrient required for healthy nerve function, red blood cell formation, and DNA synthesis

Elsevier, Inc

i.p.) or 2IM for 2 weeks (n = 6)

Experiments performed in differentiated SH-SY5Y neuroblastoma cells have shown that exposure to PS-NPs downregulates expression of the CI subunit NDUFB8, leading to diminished basal and maximal oxygen consumption rates alongside increased proton leakagefurther confirming mitochondrial CI dysfunction 32