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At certain times in their life, such as pregnancy, post-partum, breastfeeding, perimenopause, and menopause, their bodies are undergoing hormonal shifts

The accumulation of NADPH autofluorescence over time is an indicator of aconitase activity, where ACO1/2 present in the sample converts the supplied citrate to isocitrate, which is subsequently metabolized by the supplied IDH1 in a reaction that yields NADPH