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Targeting mitochondrial induces apoptosis Previous studies focusing on the regulation of mitochondria in apoptosis indicated that pro-apoptotic proteins translocate to the mitochondrial outer membrane and trigger the source of reactive oxygen species (ROS) and apoptosis directly

strain ADP: effects of toxicity and adaptation

While this offers little hard information on flux through the various steps, it is consistent with glutathione making a relatively small contribution to ascorbate regeneration, all the more so if GR also has to maintain GSH oxidized by DHA-independent processes

Jandial R, Neman J, Lim PP, Tamae D, Kowolik CM, Wuenschell GE, et al

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