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Louandre C, Ezzoukhry Z, Godin C, Barbare JC, Mazire JC, Chauffert B, Galmiche A

Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase

Wu C, Pan LL, Niu W, Fang X, Liang W, Li J, et al

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FSP1 can inhibit ferroptosis by reducing ubiquinone or CoQ to ubiquinone or CoQH 2 on the cell membrane, with the latter functioning as an antioxidant that trap radicals and thus prevents lipid peroxidation, thereby preventing ferroptosis (Fig