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Irritable bowel syndrome pathophysiology studies draw attention to the importance of bacteria through fecal transplantation experiments from patients with IBS-C and IBS-D to germ-free (GF) animals

The vitamin B12TCN2 receptor, CD320, is downregulated in the brains of MS patients: this can then be restored by fingolimod that functionally antagonizes S1P1 and upregulates CD320, Chun and Kihara explained

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