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Notably, in the present study, GPx1 depletion induced the hyperactivation of JNK in HeLa and MDA-MB-231 cells

Under healthy physiological conditions, the three most abundant SCFAs: acetate, propionate and butyrate, are synthesised in the ratio of 60:20:20, with the combined concentration of the three reaching approximately 100mM in the human gut lumen, with much lower levels detected in systemic circulation [93]