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The activity of enzyme POD in cold stored mango fruit was also significantly increased by aqueous ozonation compared to untreated control (Table 3)

Research suggests it participates in detoxification, peroxide reduction, and redox signaling by serving as a cofactor for glutathione-dependent enzymes

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Fernndez-Lzaro D, Arribalzaga S, Gutirrez-Abejn E, Azarbayjani MA, Mielgo-Ayuso J, Roche E

Munc13-4 polymorphism is associated with MAS, sJIA and systemic inflammation, while chronic TLR9 stimulation in mice develops features characteristic of MAS, including elevated serum levels of IFN, interleukin 6 (IL-6) and hepatic inflammation 10