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doi: 10.1046/j.1365-2958.2003.03634.x 143 JosephB.Schneiker-BekelS.Schramm-GlockA.BlomJ.ClausH.LinkeB.et al

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the liposomes may be sized so that some fraction of them are between about 20 to100 nm in diameter

Supporting this, increased nitrotyrosine staining, an indicator of peroxynitrite-mediated protein damage, has been detected in sputum macrophages from COPD patients and correlates with worsened lung function [87]