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Indeed, recent studies have revealed that the activation of the PI3K/Akt/mTOR pathway can induce autophagy via dephosphorylation of mTOR in several cell types 77,78

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During the active stage of ischemia and the response of late-response genes, i.e., 24 h after pMCAO, we observed increased levels of transcripts encoding transmembrane receptors and enzymes, especially cytokines and immunoglobulins

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