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Metabolic measurements including body composition, indirect calorimetry and BAT thermogenesis were performed on a day when all mice were in a fed state

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[28] [29] Selective Pressure and Enzyme Evolution [edit] The atmospheric accumulation of highly reactive O 2 likely exercised a strong selective pressure against anaerobic organisms, and led to the adaptive evolution of oxygen utilization in metabolism (Boden et al

elegantly demonstrated that proliferating cells ferment glucose to lactate when shuttle flux becomes saturated 186