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10.1016/j.cbpc.2023.109663 69 JiangG.ZhangL.WangH.ChenQ.WuX.YanX.et al (2017)

cell Biochem

GPX4 also exhibits activity to inhibit inflammatory NFKB pathway activation and proinflammatory mediator production (e.g., production of IL1B and PTGS2/COX2 [prostaglandin-endoperoxide synthase 2]) in various experimental models, such as angiogenesis and hair follicle development [25,178]

Generally, it is believed that urolithiasis, the process of stone formation in the urinary tract, causes crystal aggregation, nucleation, and growth of insoluble particles [7]