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Studies have shown that glutathione supplementation can increase both red blood cell GSH levels and reduce free radical damage in pregnant women

Among these, bortezomib is a proteasome inhibitor that induces ROS and ER stress in head and neck squamous cell carcinoma cells 112 , and celecoxib, a nonsteroidal anti-inflammatory drug, aggravates ER stress and induces apoptosis by altering the Bax/Bcl-2 ratio and increasing ROS in prostate cancer cells 113

Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis

doi: 10.1007/s10753-014-9887-0 127 ChenJWuHWangQChangYLiuKWeiW

doi: 10.1002/bmc.247 79