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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood

A lethal dose of alcohol varies depending on factors like age, weight, and health

Furthermore, it should be administered with caution in patients with renal impairment, as it may heighten the risk of adverse reactions