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As such, the formation of the hydroquinoneGSH conjugate cannot be considered as a detoxification mechanism itself, causing the resulting adducts to be nephrotoxic and myelotoxic

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Additionally, the intracellular GSH was not changed at 12 hours between control and CSE but by 24 and 48 hours there was significantly increased intracellular GSH in the CSE exposed cells (Figure 1B)

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Moreover, the gut microbiota affects behavior, regulates neurotransmitter production in the gut and brain, and plays a role in brain development and myelination patterns (Bolyen et al., 2019