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Results showed that vB12 treatment had a strong effect on both genotypes (Fig S4B and C)

In the future, novel treatment approaches will need to be directed towards increasing the bioavailability of plant chemicals by ultra-modern delivery mechanisms like nanoformulations, phytosomes, and controlled-release technologies

Vitamin B12 helps generate DNA as well as red blood cells

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The methodological quality of the included studies, as assessed through the Jadad and NewcastleOttawa scales, varied from moderate to high, while the GRADE assessment indicated moderate certainty of evidence for serum vitamin B12 increase and low certainty for homocysteine reduction