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Glyoxalase 2 Is Involved in Human Prostate Cancer Progression as Part of a Mechanism Driven By PTEN/PI3K/AKT/mTOR Signaling With Involvement of PKM2 and ERalpha

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Similarly, oral exposure to AgNPs (0, 1, 5, 10, 25, 50 mg/kg bw/day for 4 weeks) induced dose-dependent toxicity in mice, evidenced by body weight suppression and reduced intestinal dendritic cell numbers, confirming that both systemic and local immune effects scale with dose (Ren et al., 2023)

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Mouse Studies All mice were intraperitonially injected with 100L tamoxifen (Cayman Chemical, 13258) on alternating abdominal sides for 5 consecutive days