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The triple agonism is achieved through a combination of conserved interactions and receptor-specific contacts within the transmembrane domain

2.2 Animals and treatments Male Sprague-Dawley (SD) rats (aged 89 weeks, 200220 g) were purchased from the Sipper-BK laboratory animal CO., Ltd

Dosing Phases & Cycling The research protocol is typically staged rather than started at full pace, and it is cycled the compound is not framed for indefinite continuous use