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doi: 10.1016/S0140-6736(20)30367-6 7

Shim HS, et al

GPX2-knockdown-induced ROS suppress gastric cancer progression and metastasis by disrupting the KYNU-Kyn-AhR signaling pathway, 98 which is known to promote metastasis, as evidenced in chronic lymphocytic leukemia (CLL) in mice

In conditions where renal blood flow is dependent upon prostaglandin synthesis, administration of NSAIDs can result in significant decreases in renal blood flow leading to acute renal failure

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