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Oncotarget (2017) 8:4087284

Schutz vor oxidativer und zellulrer Alterung : GHK-Cu bt zytoprotektive Effekte aus, indem es freie Kupferionen chelatisiert und oxidative Schden an Lipiden, Proteinen und DNA reduziert

In a cohort study of 38 children with congenital cataracts, a missense mutation in CYP51A1 was identified in one family [79]

This process not only directly generates excessive ROS by initiating the non-enzymatic Fenton reaction but also enhances the activity of lipoxygenase (ALOX) or EGLN prolyl hydroxylases (also known as PHD) [1, 19, 20]