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Clinical utility of a myelosuppressive switching agent

According to this model, the ER would constitute a trap for cellular glutathione, which is reminiscent of the mechanism of osmosis where an impermeable metabolite drives the diffusion of a permeable metabolite across a selectivity barrier such as a biological membrane. [12]

But "matters less" does not mean "does not matter at all." The initial 24 to 72 hours after injection represent a distinct pharmacokinetic phase where drug levels are rising rapidly

She'd been running on four hours of sleep, but her skin looked like she'd just returned from a spa weekend

10.1161/ATVBAHA.114.304023 138 Martnez-ReyesI.ChandelN