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Moreover, TNTs can be optimized as fundamental carriers by changing their physical characteristics (such as diameter and length) and employing alternative delivery methods to enhance their delivery capacities [288, 289]

Conversely, lipophagy promotes ferroptosis by degrading lipid droplets and releasing free fatty acids ( 2.5 Ferroptosis and metabolic reprogramming 2.5.1 Mitochondrial metabolism and ferroptosis Mitochondria are the central organelles for cellular energy metabolism

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Darula Z

Our analysis reveals critical molecular pathways, including NF-B and JNK signaling, that fundamentally compromise metabolic function