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The Nrf2/ARE signaling pathway counteracts ischemiareperfusion injury by enhancing endogenous antioxidant defense factors and suppressing ROS production during reperfusion, which indicates that enhanced antioxidant properties can protect neurons (Young Park et al., 2019), and more importantly, NRF2 plays a key role in mediating iron/hemoglobin metabolism

GaoPZhangHDinavahiRLiFXiangYRamanVet alHIF-dependent antitumorigenic effect of antioxidants in vivo

[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Yang Y., Tang H., Zheng J., Yang K

Shelf life: 24 months when stored correctly

To further verify carbon recycling during oxidative burst, we applied 3- 2 H-glucose tracing