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E.g., if a receptor has more than one binding site for a ligand, a ligand having low affinity can be useful for targeting the microvascular endothelium

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Tregs in T1D T1D is the most prevalent autoimmune disease in humans and is caused by the immune system targeting insulin-producing -cells, resulting in impaired insulin secretion and ineffective glucose utilization, ultimately leading to hyperglycemia

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10.7759/cureus.39498 [DOI] [PMC free article] [PubMed] [Google Scholar] 263.Daneshpazhooh M, Nikyar Z, Hesari KK, Rostami E, Jamshidi ST, Mohaghegh F