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PMID: 18025815

The genes identified in a recent GWAS highlight the importance of both previously recognized and novel mechanistic pathways including complement activation, collagen synthesis, lipid metabolism/cholesterol transport, receptor-mediated endocytosis, and extracellular matrix organization 24

Hydrazinolysis Intermediate 1 undergoes hydrazinolysis with hydrazine hydrate, followed by filtration to yield Intermediate 2 (the hydrazide derivative)