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Although these in vivo imaging studies do not directly demonstrate that microglia are activated (e.g., additional highly specific microglial ligands are needed to confirm the PBR imaging data) they do support the idea that glial activation is ongoing in PD patients

(2021) 13(5):e15065

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Theyre often given to people with certain health issues or who follow special diets

Animal data on LR3 infusion in pigs showed continued suppression of plasma growth hormone (~23% decrease) and IGFBP-3 across the 4-day infusion window (Tomas et al., 1997) by days 8-10 of a 10-day human community protocol, this kind of HPG-axis suppression would be expected to be active