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This project was also partly supported by Czech Science Foundation, project P301-12-1503

Association analyses using WES data, PGS for BMI and the comparison of MC4R carriers in the GOOS with noncarriers in the UK Biobank across cardiovascular and metabolic traits were conducted under UK Biobank application ID no

Omega-3 fatty acids and EPA (eicosapentaenoic acid), in particular, are well documented inhibitors of pro-inflammatory cytokines such as tumor necrosis factor- (TNF-)

Overall, rational integration of virus-targeted drugs with PCD modulation strategies requires systematic evaluation of mechanistic synergy, immunological consequences, and optimal intervention timing to maximize clinical benefit