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Glutathione (GSH) is made in all cells in the body, however, it plays a key role in detoxification in the liver (1)

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Apoptosis is an active, programmed mode of cell death, while necrosis is classically defined as uncontrolled, accidental cell death ( In recent years, there has been an increasing recognition of the importance of non-apoptotic cell death mechanisms in elucidating the molecular processes that regulate cell death

The cytosolic Grx1-roGFP2 and to a lesser extent the plastidic TKTP-Grx1-roGFP2 lines exhibited lower fluorescence intensity when excited at 488 nm after 24 h or 48 h of AITC treatment compared to their respective control, indicating oxidative conditions and/or lower levels of glutathione (Fig