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doi: 10.3390/antiox11020371 87 CiumrneanLMilaciuMVRuncanOVesaCRchianALNegreanVet al

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To further characterize the pharmacology of the kratom alkaloids, competitive radioligand binding assays were conducted with HEK293 cells stably expressing -, - and -opioid receptors to assess the affinity of the alkaloids at these receptors (Table 2)