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Supplements which are generally considered safe can have side effects in large doses, or when the upper limit is exceeded, especially when that nutrient can be stored in the body

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Sulfur-Rich Foods: Since cysteine contains sulfur, eating foods like garlic, onions, and cruciferous vegetables (broccoli, kale, Brussels sprouts) provides the raw materials your body needs

I do think testing is another case where that might be a case where you could use a high dose CoQ10 to try to stimulate more mitochondria if testing shows that you dont have enough and thats your limiting bottleneck