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J Cardiovasc Pharmacol (2021) 78:e309

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Additionally, autophagy deficiency impedes the release and secretion of crucial cytokines and chemokines involved in T cells and DC recruitment, including IFN- , CXCL9, CXCL10, and CXCL11, thus immune surveillance escape occurred (Table 1) (60)

PRP, on the other hand, is anabolic it delivers active growth factors that recruit stem cells, stimulate fibroblasts, and encourage the formation of healthy new collagen

The comprehensive analysis combined with ChIP-seq and gene expression microarray data sets further indicates that these acetylation events at TSS are significantly related to the expression of their target genes, many of which are involved in cancer-related pathways in the neuronally expressed developmentally down-regulated 4 (NEDD4)-dependent manner