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Immunofluorescent stainings For staining of tissue sections, human and murine lung tissue was fixed in 4% formalin prior to paraffin embedding

Zhou Y, Wang Z, Huang Y, Bai C, Zhang X, Fang M, Ju Z, Liu B (2022c) Membrane dynamics of ATG4B and LC3 in autophagosome formation

What a Herxheimer Reaction Feels Like Patients experiencing a Herxheimer reaction may report: Increased fatigue Worsening brain fog Muscle or joint pain Flu-like symptoms Sleep disruption Dizziness or head pressure Mood shifts or anxiety These symptoms can resemble a flare-up or relapse, which adds to the confusion

Each main group (healthy and tumorized) was divided into four subgroups for treatments with free curcumin (FC), non-targeted dendrimeric curcumin (DC), mitochondria-targeted dendrimer without curcumin (TD), mitochondria-targeted dendrimer with curcumin (TDC), and PBS as the control group

The authors consider central hypothyroidism (suboptimal TSH production) to be extremely rare, limited to cases of obvious HP disease or damage (~1 in 100,000 persons)