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Description

Inside the cell, cystine is reduced to cysteine, a precursor of GSH and an indispensable cofactor for GPX4 activity

Apoptosis describes a programmed mode of cell death that is characterized by a series of biochemical events that ultimately lead to cell fragmentation into compact membrane-enclosed structures, called apoptotic bodies that are taken up by neighboring cells and phagocytes, preventing inflammation, and tissue damage (Taylor et al., 2008)