glutathion perfusion de Protein S-glutathionylation in redox signaling A. Mitochondrial redox Glutathione in the Brain

This results in a substantial buildup of hydrogen peroxide in the cytosol, which works to reversibly oxidize catalytic cysteine residues in phosphatases, ultimately preventing them from dephosphorylating key downstream TCR signaling proteins, including ZAP-70, PTEN, and LAT (75, 76)

Figure 1 Polyphenols are a diverse group of plant secondary metabolites broadly categorized into flavonoids and non-flavonoids

Lioy, D

10.1016/j.yexcr.2017.01.017 22 CluverC

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