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3.2.2 SIRTs in chronic kidney disease 3.2.2.1 SIRT1 Diabetic kidney disease

Mutational analysis of serine 83 or serine 96 in the androgen receptor NH 2 -terminal domain abolishes this up-shift indicating that phosphorylation of these serine residues likely contributes to the phosphorylation of the 112 kDa androgen receptor isoform (70, 183)