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doi: 10.3389/fcell.2024.1435125 Received 19 May 2024 Accepted 27 June 2024 Published 11 July 2024 Volume 12 - 2024 Edited by Takehito Ouchi, Tokyo Dental College, Japan Reviewed by Kui Xu, Anhui University of Chinese Medicine, China Xiaolei Li, University of Pennsylvania, United States Updates Copyright 2024 Zheng, Liu, Sun and Meng

16 and Supplementary Fig

(2011) 3:a004457

Moreover, IGF1R deficiency in mice reduced tumor growth, proliferation, inflammation and vascularization, and increased apoptosis after tumor heterotopic transplantation