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The authors concluded that CoQ10 deficiency is a major risk factor in the pathophysiology of ME/CFS

doi: 10.1016/j.ijcard.2014.11.034 151 QuinCEstakiMVollmanDMBarnettJAGillSKGibsonDL

Second, we supplemented worms with commercially available ceramides containing different lengths of acyl chains and found that C22 ceramide (the ceramide containing BA, d18:1/22:0) and C24 ceramide (d18:1/24:0) restored the activity of gst-4p ::GFP in sptl-1 RNAi-treated worms (Fig