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In a 3-month study of 23 cystinosis patients less than 18 years old without renal replacement therapy, the addition of oral NAC 25 mg/kg/day to their cysteamine standard of care was associated with a reduction in oxidative stress (based on decreased serum thiobarbituric acid-reactive substances (TBARS) (p NAC

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The lysosomal transcription factor TFEB represses myelination downstream of the Rag-Ragulator complex

However, specific patient populations such as individuals with mutations in their glutathione synthesizing enzymes, AIDS patients, and cystic fibrosis patients can benefit from glutathione supplementation (Ashley, 2018)

They also help reduce inflammation, making it easier for the skin to heal properly without excessive scarring