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While polygenic risk scores (PRS) address part of this architecture by aggregating validated risk alleles from GWAS, the proposed workflow further considers the potential cumulative burden of variants typically deemed benign, aiming to bridge the gap between population-level risk estimation and individualized interpretation (Torkamani et al., 2018)

Proinflammatory cytokines and oxidative stress can precipitate disrupted synaptic function, exacerbating neuronal vulnerability and accelerating degeneration [67]

Glutathione Glutathione is a tripeptide comprised of three amino acids: Cysteine, glutamic acid, and glycine

Advances in drug screening technologies, such as computer simulations and artificial intelligence (AI), have significantly accelerated the drug discovery process

Prevalence, awareness, treatment and control of hypertension, diabetes and hypercholesterolemia, and associated risk factors in the Czech Republic, Russia, Poland and Lithuania: a cross-sectional study