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ALA acts as a cofactor for pyruvate dehydrogenase and -keto-glutarate dehydrogenase activity (Schmidt et al., 1994), and is also required for the oxidative decarboxylation of pyruvate to acetyl-CoA, a critical step bridging glycolysis and the citric acid cycle (Reed, 1998)

10.1038/s41372-023-01627-2 41

doi: 10.1111/acel.12937 48 Cohen-SalmonM.SlaouiL.MazarN.GilbertA.OudartM.Alvear-PerezR.et al

Changes over the fermentation period in phenolic compounds and antioxidant and anticancer activities of blueberries fermented by Lactobacillus plantarum