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Methemoglobinemia occurs when this enzymatic reduction is overwhelmed by an exogenous oxidant stress, such as a drug or chemical agent ( Table 207-1 )

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These tools can also be applied to DNA methylation data generated by Nanopore sequencing

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Drug interactions : Individuals taking medications that affect nitric oxide pathways or blood flow should exercise particular caution, as theoretical interactions are possible, though unconfirmed in clinical settings