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However, oral vitamin B 12 can be absorbed passively independent of intrinsic factor

As research continues to reveal new applications and mechanistic insights, this compound stands poised to contribute to breakthrough discoveries across the expanding landscape of metabolic biology and translational research

While the condition is the major cause of poor vitamin B 12 status in the elderly population, it is usually associated with atrophic gastritis, a chronic inflammation of the lining of the stomach that ultimately results in the loss of glands in the stomach (atrophy) and decreased stomach acid production (see Atrophic gastritis)

There is no consensus on the interpretive criteria used to define inadequate B12 status with these B12 biomarkers

Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications