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doi: 10.3389/fonc.2018.00331 88

Obidoxime is determined directly in a diluted sample solution by reversed-phase HPLC using sodium 1-heptanesulfonate as a counter ion in the mobile phase

465 The anterior cingulate cortex, essential for emotional pain processing, shows increased blood flow in patients with PDPN, a hyperperfusion state that normalizes following duloxetine treatment

Additionally, it upregulates the gene expression levels of several antioxidant enzymes, thus indirectly enhancing the cellular antioxidant capacity (161,162)