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Overall, the contradictive roles of FasL and mFasL require more studies to investigate the potential roles of FasL/mFasL modulation in future neuroprotective treatments

Nature (2010) 468(7327):111923

Journal of Investigative Dermatology .Read source Pickart L, Vasquez-Soltero JM, Margolina A (2015)

Protopine protects chondrocytes from undergoing ferroptosis by activating Nrf2 pathway

Building on the foundation of PD-1/CTLA-4 inhibition, targeting the next generation of immune checkpoints, including LAG-3, TIGIT, and Tim-3, represents a pivotal strategy to counteract adaptive resistance by more comprehensively reversing T-cell exhaustion [333,334,335,336,337]