Glycated RBCs are also more sensitive to oxidative stress, which injures the lipid bilayer and shortens the life span of the cell
10.33549/physiolres.931913 Glossary ENaCalpha epithelial sodium channel5-HTserotoninACEangiotensin converting enzymeACEIangiotensin converting enzyme inhibitorAchacetylcholineADHanti-diuretic hormoneADMETabsorption, distribution, metabolism, excretion and toxicityALTalanine transaminaseAngangiotensinARarteriolar resistanceARBangiotensin receptor blockerASatherosclerosisASTaspartate aminotransferaseBBbeta-blockerBKbradykininBMIbody mass indexBPblood pressureCacalciumCAcardiac arrhythmiaCAIcarbonic anhydrase inhibitorcAMPcyclic adenosine monophosphateCBVDcerebrovascular diseaseCCcalcium channelCCBcalcium channel blockercGMPcyclic guanosine monophosphateCHDcoronary heart diseaseCHFcongestive heart failureCHTcardiac hypertrophyCOcardiac outputCOXcyclooxygenaseCRCconcentration-response curveCVcardiovascularCVDcardiovascular diseaseCVScardiovascular systemDAGdiacylglycerolDBPdiastolic blood pressureDLdyslipidemiaDMdiabetes mellitusDPP-4dipeptidyl peptidase-4ECsendothelial cellsEDHFsendothelium-derived hyperpolarizing factorsEDRFendothelium-derived relaxing factorEDVend-diastolic volumeEFendothelial functioneNOSendothelial nitric oxide synthaseETendothelinFAsfatty acidsFDAFood and Drug AdministrationFMoHFederal Ministry of HealthFTIRfourier-transform infraredGABAgamma-aminobutyric acidGFRglomerular filtration rateGRASgenerally regarded as safeGTglucose toleranceH 2 Shydrogen sulfideHAheart attackHbA1chemoglobin A1c (Glycated hemoglobin)HChypercholesterolemiaHDLChigh-density lipoprotein cholesterolHFheart failureHO-1heme oxygenase 1HPhyprepolarizationHRheart rateHTNhypertensionICAM-1intracellular adhesion molecule 1IKK-Binhibitor of the nuclear factor kappa-B sub-unit betaiNOSinducible nitric oxide synthaseINRinternational normalized ratioIP 3 inositol-1,4,5-triphosphateIRinsulin resistanceIRS-1insulin receptor substrate 1KpotassiumLC 50 median lethal concentrationLD 50 medial lethal doseLDLClow-density lipoprotein cholesterolLFTliver function testMAPmean arterial blood pressureMCmyocardial contractilityMCVmean corpuscular volumeMImyocardial infarctionmiRNAmicroRNAMPmedicinal plantMSmetabolic syndromeNAnoradrenalineNCDsnon-communicable diseasesNEnorepinephrineNKCCNa + /K + /2Cl - co-transporterNOnitric oxideNOAELno-observed-adverse-effect-levelNOELno-observed-effect levelNrf2nuclear factor-erythroid 2 related factor 2NSnephrotic syndromeOSoxidative stressPDEphophodiesterasePEphenylephrinePGprostaglandinPI3-k/Aktphosphotidylinositol 3-kinase (Protien kinase B)PKCprotein kinase-CPNSparasympathetic nervous systemPPARperoxisome-proliferator-activated receptorsPTprothrombine timePVDperipheral vascular diseasePVRperipheral vascular resistanceRAASrenin-angiotensin-aldosterone systemRBCrRed blood cellRCTrandomized control trialRIrenal insufficiencyROCCreceptor-operated calcium channelROSreactive oxygen speciesRSnHhydropolysulfideRxtreatmentsGCsoluble guanylyl cyclaseSHRspontaneously hypertensive ratSMsmooth muscleSNSsympathetic nervous systemSVstroke volume,T2DMType 2 diabetes mellitusT3triiodothyronineT4thyroxineTCtotal cholesterolTGtriglycerideVCAM-1vascular cell adhesion molecule-1VDvascular dysfunctionVDCCvoltage-dependent calcium channelVFvascular functionVGCCvoltage-gated calcium channelVRvenous returnVSCCvoltage-sensitive calcium channelVSMCsvascular smooth muscle cellsWBCwhite blood cellWHOWorld Health OrganizationZnzinc Summary Keywords hypertension, medicinal plants, pharmacological, anti-hypertensive, nutraceuticals, compounds, policy, Ethiopia Citation Nureye D, Tadege G, Dubale S, Kebebe D, Suleman S and Nguelefack-Mbuyo EP (2025) Medicinal plants administered to control hypertension in Ethiopia: ethnomedicine, pharmacology, nutraceutical, phytochemistry, toxicology, and policy perspectives
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Fisetin is an antioxidant that has been found to reduce the burden of senescent cells these are zombie cells that have lost the ability to divide, but refuse to die
Contributing factors include: Lack of trained neurologists or movement disorder clinics
