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But the same process can also supply blood to abnormal cells

These changes create self-reinforcing pathological cycles that worsen tissue function and promote systemic insulin resistance (1517)

XW: Investigation, Writing original draft

Note that these observations are based on case reports, and do not necessarily reflect susceptibility of these demographics to toxicity (Amar 2007)

As expected by the increased striatal DA, pathways signifying activation of signalling by G-protein-coupled receptors, transmission across chemical synapses and calcium signalling were all positively enriched at 3 months in iSPN + mut (Supplementary Table 1a), whereas genes associated with metabolic pathways such as oxidative phosphorylation (OxPhos) and respiratory electron transport ATP synthesis were significantly downregulated in iSPN + mut compared to iSPN+wt at 3 months (Fig