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doi: 10.1080/1028415X.2021.1932242, 112

Self-assembled daunorubicin/epigallocatechin gallate nanocomplex for synergistic reversal of chemoresistance in leukemia

( Chitosan, a product of the N-deacetylation of chitin, possesses various advantages inherent to natural substances, such as biocompatibility, biodegradability, as well as non-toxicity and antimicrobial properties

However, the postoperative local recurrence rate is high, approximately 40%65%, and the distant metastasis rate is also considerable, approximately 40%68% (7, 8)