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More recently, a family of potent and highly selective mechanism-based suicide substrate inhibitors were developed and shown to promote the irreversible inhibition of gut microbiotadependent generation of TMA, suppression of host TMAO levels, and, in parallel, inhibition of platelet hyperresponsiveness and thrombosis potential in animal models (22)

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Transfection of fluorescent LC3 constructs The plasmids of pEX-GFP-hLC3WT and Ds-RFP-GFP-LC3 (pQCXI Puro DsRed-LC3-GFP) used in the present study were provided by Drs

[DOI] [PubMed] 31.Berezhnov AV, Fedotova EI, Nenov MN, Kasymov VA, Pimenov OY, Dynnik VV