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The conservation of the orthologs to GSTE14 in other insects attests to an essential function, which merits further biochemical investigations

Ferroptosis of retinal cells, such as RPE, photoreceptor, and RGC, has been reported to be involved in the progression of age-related/inherited macular degeneration, blue light-induced retinal degeneration, glaucoma, DR, and retinal damage caused by retinal ischemia-reperfusion (I/R) (Figure 1

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A reductase at the root cell membrane in dicots reduces Fe and potentially Cu prior to assimilation ( Plants may reduce harmful substances (e.g., HMs) through a process called in situ reduction, which can be advantageous for phytoremediation by helping to detoxify the environment (Kafle et al., 2022)