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Group (2): positive control received 15 mg/kg AZA orally

yield berberine, an isoquinoline quaternary ammonium alkaloid with notable biological efficacy (Wu et al., 2019

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Glossary VOCABULARY luminogens those nonemissive as molecules but emissive under appropriate conditions, e.g., as aggregates AIE luminogens (AIEgens) nonemissive or weakly emissive in their single molecular state but strongly emissive in the aggregate state Stokes shift the difference between the spectral position of the maximum of the first absorption band and the maximum of the fluorescence emission and can be expressed in either wavelength or wavenumber units precision medicine sometimes known as personalized medicine, is an innovative approach to tailoring disease prevention and treatment that takes into account differences in peoples genes, environments, and lifestyles theranostics the integration of diagnosis and therapy in a single platform limit of detection (LOD) the lowest concentration that can be measured/detected with statistical significance by means of a given analytical procedure Author Contributions & Haoran Wang and Qiyao Li contributed equally

As long as mTORC1 is active, ULK1 remains off, and autophagy is blocked