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Both RNP complexes were transfected into 888-Mel melanoma cells using lipofectamine CRISPRMAX (cmax00008, Invitrogen)

Its biological activity stems from its dual role as a potent antioxidantscavenging reactive oxygen species (ROS) and upregulating endogenous antioxidant enzymesand as a metabolic regulator (84, 85)

Severe (e.g., colitis , pneumonitis , hepatitis): May require holding immunotherapy and starting high-dose corticosteroids

Se trata de un pptido natural unido al cobre, compuesto por tres aminocidos (glicina, histidina y lisina) y un ion de cobre